Jack Schroder ☀️🧬
@jack_schroder_
Retweeting this again because it's one of the most important concepts to grasp. And it's such a beautifully written post. Your mindset is everything. When we feel stressed, fearful, or have buried trauma—our body enters a hypoxic state, and our mitochondria stop working properly. This leads to a drop in the production of water (dehydration), CO2 (oxygenation), and ATP (unfolding proteins to allow water to bind for its quantum properties). 2/3 of the water in us is found intracellularly; this tells you a lot about how important mitochondrial function is, on top of membrane aquaporin (AQP) channels, which are circadian regulated. Our body also enters something called the cell danger response (CDR) where extracellular ATP (eATP) gets released by the cell and acts on its various purinergic receptors (P2X/P2Y) which triggers a cascade of inflammatory events, followed by the resurrection of the cells and tissue. Fear, stress, and/or trauma has the power to do this. eATP is often released in response to cellular stress, damage, or mechanical strain. Once outside the cell, it can act as a danger-associated molecular pattern (DAMP), signaling other cells, especially in the context of inflammation, immune response, or healing after injury. Trauma can also be stored in our water networks and leads to the decoherence of our quantum system, leading to the inability to shuttle both energy/information. This causes thermodynamic inefficiency and a loss of molecular, cellular, and systemic signalling = low redox. Our cerebrospinal fluid (CSF) is directly tied to many regions of our brain throughout the interfascial water networks, as well as in the lateral, third, and fourth ventricles of the brain that meet with many important brain regions. This water is what brings the power of our external environment to our internal environment; provided our mindset is optimized. This CSF is found at the surface of the hypothalamus, brainstem, hippocampus, mammillary bodies, and many more—however, these are all closely associated with the memory, emotional processing, hormone control and autonomic nervous system function. The hypothalamus directly ties in with the limbic system where the amygdala controls our perception of fear. Buried trauma is extremely costly to our resources and requires a ton of energy input—so that trauma never "wakes up". Rapidly burning through magnesium, GABA, chloride, taurine, melanin, dopamine, oxytocin, and other metabolites. Disease will start to occur in other regions of body, despite nutrition, lifestyle, and movement factors being on point. It starts and ends with the mind being optimized to be able to process, release, and transform these stored traumas—ultimately restoring coherence, energy/information flow, near-zero entropy, and overall health at the deepest levels.
When we're in a calm, alert, and safe state, our prefrontal cortex (PFC) takes charge of regulating behavior, thoughts, and emotions. It acts as the brain's conductor, connecting to key areas like the amygdala, basal ganglia, and brainstem, including neurons that release catecholamines. In this balanced state, there's a moderate release of catecholamines, like norepinephrine (NE), with precise bursts of activity from the locus coeruleus (LC) in response to relevant stimuli. Moderate NE levels/firing activate high-affinity alpha-2A receptors, which enhance PFC function while dampening amygdala activity. These receptors also reduce the constant firing of LC neurons, allowing the PFC to guide brain and behavior with clarity and purpose. Dopamine also has this effect, where D2 dopamine receptors are activated during tonic firing, compared to phasic firing being more geared towards D1.
During uncontrollable stress, the brain releases high levels of catecholamines, which weakens the function of the prefrontal cortex (PFC) and strengthens the emotional responses of the amygdala, as well as habitual behaviors driven by the basal ganglia. The amygdala plays a key role here, not only activating catecholamines during psychological stress but also coordinating other stress responses (e.g., signaling to the periaqueductal gray). It triggers the locus coeruleus (LC) via corticotropin-releasing factor (CRF), increasing its constant firing. Elevated norepinephrine (NE) levels engage lower-affinity alpha-1 and beta receptors, which further enhance the amygdala's response while suppressing PFC function. This creates a vicious cycle, where primitive circuits take control, overriding thoughtful regulation of behavior. This chronically raises dopamine/norepinephrine levels shifting the brain into a more fear-based neural state. This chronically degrades melanin and depletes catecholamine status. When melanin is missing then redox drops significantly, water chemistry is altered, and collagen networks also break down due to the effect of CRF/ACTH/cortisol.
If there's high concentrations of deuterium (D+) within the CSF then this creates huge problems. Any water that's rich in D+ leads to disrupted hydrogen bonding, less solar light absorption, and a large decrease in the dielectric constant—leading to less charge stored in the system. This also affects the exclusion zone of the CSF which leads to inefficient shuttling of nutrients, toxins, and metabolic waste throughout the neural tissue, and into the lymphatic system.
Chronic stress and buried trauma actually leads to D+ retention due to its effects on melanin, cortisol, aldosterone, vasopressin, prolactin, and mitochondrial dysfunction. Melanin aids in D+ depletion through its chelating abilities. Hence strong UV light yields high melanin stores. Cortisol, aldosterone, vasopressin, and prolactin all increase water retention and can prevent urine/stool excretions, trapping D+ in the body for longer than it should, provided it's been packaged into urea and/or bile. When D+ accumulates chronically in the mitochondrial matrix it will significantly impair TCA/urea cycle dynamics, which alters D+/H+ ratio and increases ROS/RNS/biophoton signalling. And as we know this also lowers CO2, ATP, and deuterium-depleted H2O. CO2 is needed to clear D+ in the first step of the urea cycle. This also lowers NAD+ and drives our cells to utilize anaerobic glycolysis which raises lactate, and leads to inefficient ATP production. Leading to further decoherence and increased acidity (protons).
Due to the effect of stress, trauma, and fear on the glucocorticoid system—this leads to a huge disruption of melatonin biology. Melatonin aids in mitochondrial, melanin, and myelin optimization. It regulates redox status, aromatase (estrogen), and also influences the leptin-melanocortin pathway. It controls autophagy-apoptosis & ubiquitination cycles which are crucial for our system to run optimally so we have all our cells and their organelles/proteins working properly. When melatonin, melanin, mitochondria, and myelin become dysfunctional, we require the optimal environmental input—both externally (light-dark cycles, nutrition, location, toxins) and internally (stress/trauma, emotions, biomechanics/breathing) to restore everything to start removing symptoms and feeling our best.
This requires un-learning/re-learning, patience, dedication, and support, as it involves re-establishing balance across multiple systems that have become dysregulated. Without addressing both the external and internal environments, the body struggles to maintain coherence, leading to persistent low energy, chronic inflammation, and unresolved symptoms. Address your trauma, or you will never unlock your full potential.
The best way to address trauma is completely individualized, it depends on what you respond best to. For me personally: meditation/praying, cognitive behavioral therapy, talking to people I trust, and breathwork were huge. Set the biochemistry up by addressing all the fundamental components for optimal health: mind, breathing, hydration, nature, light, sleep, nutrition, movement, and connection. This sets the stage for your body to process/release any stored trauma that won't budge. https://x.com/therawsol/status...