Published: September 2, 2025
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💥 I’m starting something new inside OpenAI! It’s called OpenAI for Science, and the goal is to build the next great scientific instrument: an AI-powered platform that accelerates scientific discovery.

We’ll look to hire a small team of academics that are (i) world-class in their field; (ii) completely AI-pilled; and (iii) great science communicators. Paired with a small team of researchers, we want to prove that AI models are ready to accelerate fundamental science—and

Scientific discovery improves everything from the quality of our daily lives to national security to global GDP. Innovation is the reason the US leads the world. Few domains hold as much promise for improving lives as science.

GPT-5 is clearly a new threshold; below are four recent examples. There are many more, not to mention things like AlphaFold from our friends at GDM.

1. GPT-5 Pro was able to improve a bound in one of @SebastienBubeck's papers on convex optimization—by 50%, with 17 minutes of thinking. https://x.com/SebastienBubeck/...

2. GPT-5 outlining proofs and suggesting related extensions, from a recent hep-th paper on quantum field theory [https://arxiv.org/pdf/2508.212...

Image in tweet by Kevin Weil 🇺🇸

3. Our recent work with @RetroBio_ , where a custom model designed much-improved variants of Nobel-prize winning proteins related to stem cells. https://x.com/polynoamial/stat...

4. @DeryaTR_ has been a non-stop source of examples of AI accelerating his biological research, such as https://x.com/DeryaTR_/status/...

I went to grad school to become a researcher in high energy physics, only to get nerdsniped into startups like so many others. I feel super fortunate now to get to combine both.

I’ll simultaneously begin working with @SebastienBubeck and the synthetic data team at OpenAI as an AI researcher to learn the craft. I’m grateful to him and his team for being willing to mentor me, and I’m eager to prove worth their time and effort!

I’m able to do this because the product and design leaders at OpenAI are amazing, and now are complemented by @fidjissimo beginning her role as CEO of Applications. OpenAI’s products have been my life since I joined, and they’re in great hands.

We’ll share more about OpenAI for Science in the coming months. In the meantime, if you’re an AI or academic researcher interested in joining us, my DMs are open.

@kevinweil I’m excited about this - good stuff Kevin

@ShaanVP 🙏 my friend!

@kevinweil 👏👏

@kevinweil How do you think about this FT article of today? https://on.ft.com/48ay8D0 Why is AI struggling to discover new drugs?

@ivobe___ I don't have a subscription sadly so I can't read it! But I do love that the bar has moved from "AI will never do anything useful" to "gosh it's just not discovering new drugs fast enough yet"

@kevinweil - dyson sphere wen? - 50% light speed travel wen? - interstellar travel wen?

@techikansh into it

@kevinweil What a great idea! I can volunteer immediately. 🙋‍♂️☺️ Incidentally, tonight I’ll post a case where GPT-5 Pro has invented a new biological method!

@kevinweil let me know if you need any Data.

@kevinweil does HVM (type theory / compiler) research fit in this?

@kevinweil It's Deepmind before Google acquisition?

@kevinweil More of this. Unbelievably cool.

@kevinweil Very exciting.

@kevinweil let's go kevin 🚀

@kevinweil this is awesome! would love to have you on my podcast to discuss. have been writing about the potential for this for a few years: https://every.to/chain-of-thou...

@kevinweil super cool kevin! if science extends to markets / on the AGI front - would love to see more markets-driven orchestration of ai labor eg https://hypersoren.xyz/posts/o...

@kevinweil Love this! What about also building large geospatial models, leveraging your experience from planet labs?

@kevinweil I love it!

@kevinweil OpenAI for Open Source when? I barely see you guys supporting open source projects :(

@kevinweil Congrats on the new role Kevin! IMHO this is the most exciting application of AI, looking forward to seeing you lead it

@kevinweil this is what i'm talking about

@kevinweil super cool - hope to see openai share a lot of things that comes out of this team!

@kevinweil Perfect role for you! Excited for humanity.

@kevinweil that sounds like a game changer. combining ai with science has limitless potential

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