2. What happens in cells when UPEs output changes. Let us just look at one system to get a small picture of what light is capable of in information transfer? @msahsorin

@msahsorin 3. When I take my doctors and patients on the deep dive of our circulatory system they enter the fascinating world of porphyrin spectra and unpack the Soret and Q bands. Let me unpack them in a way that’s clear and straightforward. Porphyrins are these incredible, flat,

@msahsorin 4. When light from ANY source hits them, and this includes endogenous UPEs I am refering to in this post, they produce a unique absorption spectrum with two key features: a sharp, intense Soret band and a set of weaker Q bands. My tribe as already nailed the basics of this

@msahsorin 5. But why do we get four Q bands instead of just one? That’s where Gouterman’s four-orbital model comes in, and I’ll break it down without getting lost in the weeds of heavy theory. Picture the porphyrin ring as a big, symmetric playground for electrons. The electrons that

@msahsorin 6. Now, when an electron gets excited by light, it can jump from either of the two HOMOs to either of the two LUMOs. In a perfect world, you might expect just one clean transition for S0 to S1, giving one Q band. But here’s the twist: the porphyrin’s symmetry and the way

@msahsorin 7. Back to your mitochondria making UPEs and your RBC porphyrins capturing the signal. Instead, the electronic states get split and scrambled by something called vibronic coupling, where the molecule’s vibrations team up with the electronic transitions. This coupling adds

@msahsorin 8. So why do we get four and not one orbitals? It’s because you’ve got two starting orbitals (the HOMOs) and two ending orbitals (the LUMOs), and their interactions, combined with the molecule’s vibrations, create four distinct energy pathways for the S0 to S1 trip. The Soret

@msahsorin 9. Where do these extra HOMO and LUMO states come from? They’re a natural consequence of the porphyrin’s large, conjugated π-system. The ring has 18 π-electrons (in its aromatic core), and quantum mechanics dictates that such a big cyclic system generates multiple molecular

@msahsorin 10. In short: the four Q bands arise from the interplay of two HOMOs and two LUMOs, split further by vibrations and symmetry effects, while the Soret band’s simplicity comes from a more unified, high-energy leap. It’s like the porphyrin is playing a four-note chord for the Q

@msahsorin 11. Now for the really smart in my class: Imagine electric charges as tiny magnets or batteries scattered around you, creating an invisible "push" called the electric field (let’s call it the "energy breeze"). Gauss's Law helps us understand how this breeze behaves. Here’s

@DrJackKruse So…fasting bad?

@DrJackKruse From a dissipative structure theory, appears like plenty of low hanging fruit alternating between seasonal feast and famine. Goes without saying that this study did not control for the light environment. So...

@DrJackKruse Oh interesting. I'm not a big fan of fasting anymore because I had negative health results, but I must admit that at times on a fast I felt great, euphoric even. And in the winter especially in the North when we're hibernating, fasting has its benefits. I need to reread this

@DrJackKruse But is it good to have larger mitochondria ?

@DrJackKruse Can you draw parallels to the Warburg Effect?

@DrJackKruse Your thread is gaining traction! #TopUnroll https://threadreaderapp.com/th... 🙏🏼@MK_Immunity for 🥇unroll

@DrJackKruse How long do you suggest fasting for and is it fasting only food or water too? Please share more specifics.

@DrJackKruse You advocate fasting so this is confusing

@DrJackKruse Is intermittent fasting ( 6-8 hour) daily eating window a good thing? Or better to eat every 8-12 hours?

@DrJackKruse Interesting hypothesis, thanks for sharing. Hopefully, someone will investigate it further soon.

@DrJackKruse so don't fast unless you want to lose energy.....

@DrJackKruse So fasting is not good for mitochondria?

@DrJackKruse @threadreaderapp unroll