Published: December 18, 2025
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This paper from Harvard and MIT quietly answers the most important AI question nobody benchmarks properly: Can LLMs actually discover science, or are they just good at talking about it? The paper is called “Evaluating Large Language Models in Scientific Discovery”, and instead

Most AI benchmarks test answers. This paper tests the process of discovery. Models must: • Form hypotheses • Design experiments • Observe outcomes • Update beliefs • Repeat under uncertainty That’s real science, not Q&A.

Image in tweet by Alex Prompter

LLMs are surprisingly good at the first step. They generate plausible, well-worded hypotheses that look exactly like something a researcher would write. But that’s where the illusion starts.

Image in tweet by Alex Prompter

Once experiments produce results, models struggle. They: • Ignore contradictory evidence • Stick to wrong theories • Rationalize failures instead of correcting them They don’t update they defend.

Image in tweet by Alex Prompter

A major failure mode: Models latch onto correlations and invent causal stories. Even when experiments explicitly break the link, the explanation doesn’t change. Fluency replaces falsification.

Image in tweet by Alex Prompter

Here’s the uncomfortable result: High scores on standard reasoning benchmarks ≠ High scores on scientific discovery tasks The correlation is weak or nonexistent.

Image in tweet by Alex Prompter

LLMs can talk science. They can’t yet: • Track hypotheses over time • Revise beliefs reliably • Learn from failed experiments Scientific intelligence is iterative, not eloquent. Until models learn that, “AI scientist” is still a metaphor. Read full paper here:

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the day they find out how to make them think and discover new science; we will get AGI.

yess, so many teams from around the globe collaborated

yes

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